The Škoda 506 was utility vehicle produced in Czechoslovakia by car maker Skoda. It was produced mainly as a classic flatbed lorry. Vehicles designated as N or ND were made ​​as buses. These were the main two body styles however there were others. Production began in 1929 and ended in 1940, 336 vehicles were produced.

The engine was a water-cooled, in-line, six-cylinder OHV unit with a displacement of between 7.3 and 8.3 litres. The engine was the same as that found in the Škoda 306. The engine had power output of between 49 and 74 kW (67 and100 hp). The 506 reached a top speed of up to 50 km/h.