The Regent V had AEC's own frontal design and concealed radiator as standard, It was fitted with an AEC engine or Gardner 6LW engine, coupled to a synchromesh or AEC Monocontrol semi- or fully automatic gearbox.
It had been purchased by a number of bus operators in the United Kingdom outside London (London Transport bought the Routemaster during that period). The chassis had also been sold to Ireland, Portugal, some African and Arab countries and also Hong Kong. Kowloon Motor Bus, the sole operator of AEC Regent Vs in Hong Kong, received a total of 210 Regent Vs with extra long wheelbase in 1960s, they had 34-foot-long bodywork (longer than contemporary British standard of 30 feet) supplied by British Aluminium Company or Metal Sections.
In 1968, the British Labour government introduced the Bus Grant which led to the British front-engined double-deckers being phased out. The last AEC Regent V entered service in 1969.