The car was identical in appearance to its predecessor, the C-1, and featured Cadillac drum brakes, worm-and-sector steering, and Oriflow shock absorbers. It was fitted with a 5426cc Chrysler V8 engine initially capable of producing 180 bhp at 4000 rpm. Compression was later increased from 7.5 to 8.6, increasing the horsepower to 220. The C-2 had a reported top speed of 152 mph.
Three blue-and-white Cunningham C2s were entered in the 1951 24 Hours of Le Mans, two of which crashed. The car driven by Briggs Cunningham and George Huntoon experienced steering failure, and the vehicle used by George Rand and Fred Wacker Jr had a faulty gearbox. The only C-2 to finish was driven by Phil Waiters and John Fitch, and ultimately received 18th place.