The Isotta Fraschini Tipo 8 is an automobile introduced in 1919 by Isotta Fraschini. The car was equipped with straight-8 engine and it was first serial produced car in the world to have such an engine.

With this car the company gained great name and success as luxury car manufacturer. The Tipo 8 was fitted with 5,9 litre straight-8 engine initially producing 80 bhp (60 kW) and soon raised to 90 bhp (67 kW). The car had top speed of around 85 mph (137 km/h) to 90 mph (140 km/h). The main rival of the car was Rolls-Royce. The Tipo 8 was offered only with bare chassis and engine for the coachbuilders.

The Tipo 8 series got two updated models: the 8A and 8B.