The Laurin & Klement ENS (also known as the 45/50 HP) was the successor of the Type EN. The car came in 1910 and was available until 1911. Like its predecessor it was available as an open 4-seater or a sedan.

The water-cooled, side-valve, four-cylinder, four-stroke engine with a T-head had a displacement of 7364 cc and a power output of 65 hp (48 kW). This accelerated the 1450-1550-pound vehicle up to 95 km/h. The power was transferred through a gearbox and a drive-shaft to the rear wheels. The chassis of the car consisted of riveted steel U-profile beams.

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