The Leyland Panther was a rear-engined single-deck bus chassis built by Leyland between 1964 and 1972. It gained a reputation for unreliability, which to some extent was common to many of the first generation of rear-engined single-deckers.

It was sold to a number of operators in the United Kingdom, Australia, Argentina, Denmark, the Netherlands, Israel and New Zealand.

The largest quantity of Panthers was purchased by the Brisbane City Council in Queensland, Australia who purchased 341 including 1 as a prototype for the replacement of that city's tramway network. Storstockholms Lokaltrafik AB, SL, in Sweden took 200 left hand drive ones with bodywork by Park Royal Vehicles. In total, over 639 Panthers were bodied as buses for UK operators, with Liverpool buying the biggest UK fleet (110), and about 700 chassis were built for export.

Panthers were also built as coaches with a high straight chassis frame (PSUR1/2), most of these being exported to Argentinian coach operators and locally bodied. 27 coaches for the UK were bodied by Plaxton, 18 went to Seamarks, Luton, one each to Soudley Valley Coaches and Bere Regis and District, four to Skills of Nottingham and three to East Yorkshire Motor Services, who had nineteen of this variant new (and one ex-Ribble) with bus outline Marshall bodies and the two other UK coaches which had Metro-Cammell bodies. Ten units went to Egged in Israel and locally bodied by Ha'argaz.