The Matra MS620 was a sports car prototype, built by Matra in 1966 for sports car racing.

The Matra MS620 was the first prototype sports car built under the leadership of Jean-Luc Lagardère built Matra. As Matra still had no separate engine, the decision was made to fit a V8 engine from British Racing Motors, which was incorporated into the lattice tube frame of the MS620. The engine had a capacity of 2 litres.

The long term goal of Matra was to entre the car at the 24 Hours of Le Mans, this was a success. The car had no hope against the 5-litre cars from Ford and Ferrari. Direct opponents for class victory were the Carrera 6 from Porsche.

Three MS620s were built. The BRM enginewas not built for such a long distance (such as Le Mans), made some unexpected visits to the box necessary. After just 31 laps, the first factory cars had a defect in the oil pump.