The NSU 10/20 PS was presented in 1907 at the International Automobile Exhibition in Berlin. The car was in production from 1907 until 1910.

It was the most powerful model in the NSU range. It was characterised by a four-speed gearbox with reverse gear and a hill brake on the gearbox. For an extra charge, the model was also available with dual ignition and with the Bosch starter system.

The cars were fitted with a four-cylinder in-line engine with a displacement of 2608cc that produced 20hp at 1,400rpm. The top speed of the 10/20PS was 70km/h. Removable wheel rims were a special new feature.