The Packard Twin Six (designed by Jesse Vincent) was introduced for 1932 and renamed the Packard Twelve for the remainder of its run (through 1939).

The car was made as a way for founder James Ward Packard to beat the stock market crash of 1932, and launched with another one of Packard's vehicles, the Eight Light, for financial purposes.

Built all the way from scratch, the Twin Six included a small bore V12 with an angle of 67 degrees. However, transaxle problems slowed down the production, so they enlarged the V12 to balance out their Deluxe Eight chassis. After a few modifications of the venturi, the finished engine included new features, such as GM hydraulic tappets and spacing between train components. It was soon able to go 100 mph.