The Penske PC-16 was a CART Penske Racing car which was constructed for competition in the 1987 season. The chassis debuted with poor results at the season opening races, and struggled mightily to get up to speed at Indianapolis. Midway through the first week of practice, the Penske team parked the PC-16 in favor of their backup cars, a contingent of March 86C chassis.

Designer Alan Jenkins was fired from Penske, and later replaced with Nigel Bennett.